Cancer Immunol Res. 2019 Feb 19. pii: canimm.0566.2018. doi: 10.1158/2326-6066.CIR-18-0566. [Epub ahead of print]
Targeted delivery of IL2 to the tumor stroma potentiates the action of immune checkpoint inhibitors by preferential activation of NK and CD8+ T cells.
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth
Article | Published: 18 February 2019
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth
Clémence Hollande, Jeremy Boussier, James Ziai, Tamaki Nozawa, Vincent Bondet, Wilson Phung, Binfeng Lu, Darragh Duffy, Valerie Paradis, Vincent Mallet, Gérard Eberl, Wendy Sandoval, Jill M. Schartner, Stanislas Pol, Rosa Barreira da Silva & Matthew L. Albert
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses
Ivana Kurelac1,2, Luisa Iommarini 3, Renaud Vatrinet1,3, Laura Benedetta Amato1, Monica De Luise1, Giulia Leone3, Giulia Girolimetti1, Nikkitha Umesh Ganesh1, Victoria Louise Bridgeman2, Luigi Ombrato2, Marta Columbaro4, Moira Ragazzi5, Lara Gibellini6, Manuela Sollazzo3, Rene Gunther Feichtinger7, Silvia Vidali 7, Maurizio Baldassarre1, Sarah Foriel8,9, Michele Vidone1, Andrea Cossarizza6,
Daniela Grifoni 3, Barbara Kofler7, Ilaria Malanchi2, Anna Maria Porcelli3,10 & Giuseppe Gasparre1,11
http://clincancerres.aacrjournals.org/content/early/2019/02/12/1078-0432.CCR-18-3016
Immunotherapeutic Blockade of Macrophage Clever-1 Reactivates the CD8+ 2 T Cell Response Against Immunosuppressive Tumors
Miro Viitala1,2, Reetta Virtakoivu1, Sina Tadayon1,2, Jenna Rannikko1, Sirpa Jalkanen13 , Maija
Hollmén
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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
Hongwei Du Koichi Hirabayashi Sarah Ahn Barbara Savoldo Soldano Ferrone Gianpietro Dotti
https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30002-9?fbclid=IwAR1A-N7qsE4fMWuETuiMDx7WtvC83m5adnt9YX1wd4DFUihlDg-nsKZrrm4
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Cancer Immunol Res. 2019 Feb 19. pii: canimm.0566.2018. doi: 10.1158/2326-6066.CIR-18-0566. [Epub ahead of print]
Targeted delivery of IL2 to the tumor stroma potentiates the action of immune checkpoint inhibitors by preferential activation of NK and CD8+ T cells.
Hutmacher C1, Núñez N2, Liuzzi AR3, Becher B3, Neri D4.
http://cancerimmunolres.aacrjournals.org/content/early/2019/02/19/2326-6066.CIR-18-0566.full-text.pdf#
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Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth
Article | Published: 18 February 2019
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth
Clémence Hollande, Jeremy Boussier, James Ziai, Tamaki Nozawa, Vincent Bondet, Wilson Phung, Binfeng Lu, Darragh Duffy, Valerie Paradis, Vincent Mallet, Gérard Eberl, Wendy Sandoval, Jill M. Schartner, Stanislas Pol, Rosa Barreira da Silva & Matthew L. Albert
https://www.nature.com/articles/s41590-019-0321-5?sf98993211=1&fbclid=IwAR1hyAQQvlHeSYlTf8jTakZsrti8TRmg60HkzPh8WqygK5kkcTOpj7m9ogI
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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma
Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, Yuan Hao, Ela Elyada, Youngkyu Park, Jonathan Preall and David A. Tuveson
http://cancerdiscovery.aacrjournals.org/content/9/2/282
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Epigenetic immune cell counting in human blood samples for immunodiagnostics
http://stm.sciencemag.org/content/scitransmed/10/452/eaan3508.full.pdf
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Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
Leonard Drees, Tatiana Königsmann, Martin H. J. Jaspers, Ralf Pflanz, Dietmar Riedel, Reinhard Schuh
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007882
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STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
Yu Hui Kang, Amlan Biswas, Michael Field & Scott B. Snapper
https://www.nature.com/articles/s41467-019-08743-8
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Matjaz Barboric’s new Mol Cell paper fresh out of oven. He wants to collaborate on p53-CDK9
P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress
Andrii Bugai, Alexandre JC Quaresma, Caroline C Friedel, Valentina Lenasi, Christopher R Sibley, Petra Kukanja, Koh Fujinaga, Melanie Blasius, Thomas Hennig, Jernej Ule, Lars Doelken, Matjaz Barboric
https://secure.jbs.elsevierhealth.com/action/getSharedSiteSession?rc=1&redirect=https%3A%2F%2Fwww.cell.com%2Fmolecular-cell%2Ffulltext%2FS1097-2765%2819%2930053-X
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A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids
https://www.nature.com/articles/s42003-019-0305-x
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https://www.nature.com/articles/s41467-019-08839-1.pdf
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses
Ivana Kurelac1,2, Luisa Iommarini 3, Renaud Vatrinet1,3, Laura Benedetta Amato1, Monica De Luise1, Giulia Leone3, Giulia Girolimetti1, Nikkitha Umesh Ganesh1, Victoria Louise Bridgeman2, Luigi Ombrato2, Marta Columbaro4, Moira Ragazzi5, Lara Gibellini6, Manuela Sollazzo3, Rene Gunther Feichtinger7, Silvia Vidali 7, Maurizio Baldassarre1, Sarah Foriel8,9, Michele Vidone1, Andrea Cossarizza6,
Daniela Grifoni 3, Barbara Kofler7, Ilaria Malanchi2, Anna Maria Porcelli3,10 & Giuseppe Gasparre1,11
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