28.11.18 General

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9 thoughts on “28.11.18 General”

  1. Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non–Small Cell Lung Cancer

    Varuna Nangia, Faria M. Siddiqui, Sean Caenepeel, Daria Timonina, Samantha J. Bilton, Nicole Phan, Maria Gomez-Caraballo, Hannah L. Archibald, Chendi Li, Cameron Fraser, Diamanda Rigas, Kristof Vajda, Lorin A. Ferris, Michael Lanuti, Cameron D. Wright, Kevin A. Raskin, Daniel P. Cahill, John H. Shin, Colleen Keyes, Lecia V. Sequist, Zofia Piotrowska, Anna F. Farago, Christopher G. Azzoli, Justin F. Gainor, Kristopher A. Sarosiek, Sean P. Brown, Angela Coxon, Cyril H. Benes, Paul E. Hughes and Aaron N. Hata

    http://cancerdiscovery.aacrjournals.org/content/candisc/early/2018/11/14/2159-8290.CD-18-0277.full.pdf

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  2. Mannose impairs tumour growth and enhances chemotherapy

    Pablo Sierra Gonzalez, James O’Prey, Simone Cardaci, Valentin J. A. Barthet, Jun-ichi Sakamaki, Florian Beaumatin, Antonia Roseweir, David M. Gay, Gillian Mackay, Gaurav Malviya, Elżbieta Kania, Shona Ritchie, Alice D. Baudot, Barbara Zunino, Agata Mrowinska, Colin Nixon, Darren Ennis, Aoisha Hoyle, David Millan, Iain A. McNeish, Owen J. Sansom, Joanne Edwards & Kevin M. Ryan

    https://www.nature.com/articles/s41586-018-0729-3

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  3. http://cancerdiscovery.aacrjournals.org/content/8/11/1458
    Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness
    Bernhard W. Renz, Takayuki Tanaka, Masaki Sunagawa, Ryota Takahashi, Zhengyu Jiang, Marina Macchini, Zahra Dantes, Giovanni Valenti, Ruth A. White, Moritz A. Middelhoff, Matthias Ilmer, Paul E. Oberstein, Martin K. Angele, Huan Deng, Yoku Hayakawa, C. Benedikt Westphalen, Jens Werner, Helen Remotti, Maximilian Reichert, Yagnesh H. Tailor, Karan Nagar, Richard A. Friedman, Alina C. Iuga, Kenneth P. Olive and Timothy C. Wang

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