8 thoughts on “JC 4.11.2015”

  1. TOPI

    RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

    Myron G. Best, Nik Sol, Irsan Kooi, Jihane Tannous, Bart A. Westerman, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Jan Koster, Bauke Ylstra, Najim Ameziane, Josephine Dorsman, Egbert F. Smit, Henk M. Verheul, David P. Noske, Jaap C. Reijneveld, R. Jonas A. Nilsson, Bakhos A. Tannous12, Pieter Wesseling12, Thomas Wurdinger12

    http://www.cell.com/cancer-cell/fulltext/S1535-6108(15)00349-9

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  2. NATURE CELL BIOLOGY | LETTER
    Lateral adhesion drives reintegration of misplaced cells into epithelial monolayers
    Dan T. Bergstralh, Holly E. Lovegrove & Daniel St Johnston
    Nature Cell Biology 17, 1497–1503 (2015) doi:10.1038/ncb3248

    Click to access ncb3248.pdf

    Just glanced this now, will try to read it but I drop it here in case Heidi doesn’t do it also 😉

    Cell Metabolism
    Short Article
    Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation
    Alex J. Bott,1,9,10 I-Chen Peng,1,8,9 Yongjun Fan,1 Brandon Faubert,4 Lu Zhao,2 Jinyu Li,3 Sarah Neidler,5 Yu Sun,1,10 Nadia Jaber,1 Dawid Krokowski,6 Wenyun Lu,7 Ji-An Pan,1,10 Scott Powers,3 Joshua Rabinowitz,7 Maria Hatzoglou,6 Daniel J. Murphy,5 Russell Jones,4 Song Wu,2 Geoffrey Girnun,3 and Wei-Xing Zong1,10,*

    http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00482-9#

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  3. An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis
    Smita Matkar, Paras Sharma, Shubin Gao, Buddha Gurung, Bryson W. Katona, Jennifer Liao, Abdul Bari Muhammad, Xiang-Cheng Kong, Lei Wang, Guanghui Jin, Chi V. Dang, Xianxin Hua
    http://www.sciencedirect.com/science/article/pii/S1535610815003360?_rdoc=1&_fmt=high&_origin=gateway&_docanchor=&md5=b8429449ccfc9c30159a5f9aeaa92ffb

    The spliceosome is a therapeutic vulnerability in MYC-driven cancer
    Tiffany Y.-T. Hsu, Lukas M. Simon, Nicholas J. Neill, Richard Marcotte, Azin Sayad, Christopher S. Bland, Gloria V. Echeverria, Tingting Sun, Sarah J. Kurley, Siddhartha Tyagi, Kristen L. Karlin, Rocio Dominguez-Vidaña, Jessica D. Hartman, Alexander Renwick, Kathleen Scorsone, Ronald J. Bernardi, Samuel O. Skinner, Antrix Jain, Mayra Orellana, Chandraiah Lagisetti, Ido Golding, Sung Y. Jung, Joel R. Neilson, Xiang H.-F. Zhang, Thomas A. Cooper et al.
    http://www.nature.com/nature/journal/v525/n7569/full/nature14985.html

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  4. Nature. 2015 Sep 17;525(7569):384-8. doi: 10.1038/nature14985. Epub 2015 Sep 2.

    The spliceosome is a therapeutic vulnerability in MYC-driven cancer.

    Hsu TY1,2,3,4, Simon LM4, Neill NJ1,4, Marcotte R5, Sayad A5, Bland CS1,4, Echeverria GV6,7,8, Sun T1,4, Kurley SJ1,4, Tyagi S1,4, Karlin KL1,4, Dominguez-Vidaña R1,2,4, Hartman JD4, Renwick A4, Scorsone K9, Bernardi RJ9, Skinner SO1,10, Jain A1, Orellana M1,4, Lagisetti C11, Golding I1,10, Jung SY1, Neilson JR2,6, Zhang XH12, Cooper TA6,7,8, Webb TR11, Neel BG5,13, Shaw CA4, Westbrook TF1,2,4.

    http://www.nature.com/nature/journal/v525/n7569/full/nature14985.html

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