One thought on “JC 17.09.2015”

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    Nutrient Competition: A New Axis of Tumor Immunosuppression
    http://www.sciencedirect.com/science/article/pii/S0092867415011162
    Highlights
    • Tumor cells and TILs compete for glucose within the tumor niche
    • Metabolic competition can drive cancer progression
    • Checkpoint blockade antibodies alter the metabolic balance in a tumor
    • PD-L1 promotes Akt/mTOR activation and glycolysis in tumor cells

    From the referred papers I will show only the following:
    Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
    http://www.sciencedirect.com/science/article/pii/S0092867415010296

    Notice the following paper about breast cancer metastasis, might have some relevant co culture techniques , in vivo imaging to follow up metastasis.
    miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-α

    Click to access onc2014412a.pdf

    Like

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