7 thoughts on “JC 23.09.2015”

  1. TOPI

    Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

    Xin Ye, Wai Leong Tam, Tsukasa Shibue, Yasemin Kaygusuz, Ferenc Reinhardt, Elinor Ng Eaton & Robert A. Weinberg

    Nature 525, 256–260 (10 September 2015) doi:10.1038/nature14897
    Received 03 December 2014 Accepted 09 July 2015 Published online 02 September 2015

    http://www.nature.com/nature/journal/v525/n7568/full/nature14897.html

    Check also this out! A model suggesting that migration still has a key role in tumor growth in addition to proliferation (Hepsin as a target!):

    A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

    Bartlomiej Waclaw, Ivana Bozic, Meredith E. Pittman, Ralph H. Hruban, Bert Vogelstein & Martin A. Nowak
    AffiliationsContributionsCorresponding author
    Nature 525, 261–264 (10 September 2015) doi:10.1038/nature14971
    Received 01 September 2014 Accepted 23 July 2015 Published online 26 August 2015

    http://www.nature.com/nature/journal/v525/n7568/full/nature14971.html

    Like

  2. ADAM10: a new player in breast cancer progression?
    Molecular Diagnostics – British Journal of Cancer (2015) 113, 945–951. doi:10.1038/bjc.2015.288 http://www.bjcancer.com
    Published online 18 August 2015
    http://www.nature.com/bjc/journal/v113/n6/full/bjc2015288a.html

    (referring to: Adaptive Immune Regulation of Mammary Postnatal Organogenesis
    Developmental Cell, Volume 34, Issue 5, 14 September 2015, Pages 493-504)
    Preview:
    The Immunology of Breast Development
    Mark A. Travis1, Charles H. Streuli2, ,
    http://www.sciencedirect.com/science/article/pii/S1534580715005493

    I also found this review can be relevant:
    Review
    Cell-penetrating peptides: strategies for anticancer treatment
    Drazen Raucher , Jung Su Ryu
    http://www.sciencedirect.com/science/article/pii/S1471491415001227

    Like

  3. NATURE MEDICINE | LETTER
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    日本語要約
    PCSK6-mediated corin activation is essential for normal blood pressure

    Shenghan Chen, Pengxiu Cao, Ningzheng Dong, Jianhao Peng, Chunyi Zhang, Hao Wang, Tiantian Zhou, Junhua Yang, Yue Zhang, Elizabeth E Martelli, Sathyamangla V Naga Prasad, Rachel E Miller, Anne-Marie Malfait, Yiqing Zhou & Qingyu Wu
    AffiliationsContributionsCorresponding author
    Nature Medicine 21, 1048–1053 (2015) doi:10.1038/nm.3920
    Received 22 February 2015 Accepted 13 July 2015 Published online 10 August 2015

    http://www.nature.com/nm/journal/v21/n9/full/nm.3920.html

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  4. Curr Protoc Pharmacol. 2013 Mar; 0 14: Unit14.23.
    PMCID: PMC3630511

    Patient-derived Models of Human Breast Cancer: Protocols for In vitro and In vivo Applications in Tumor Biology and Translational Medicine

    Yoko S. DeRose,1,* Keith M. Gligorich,2,* Guoying Wang,1 Ann Georgelas,3 Paulette Bowman,3 Samir J. Courdy,4 Alana L. Welm,1,5 and Bryan E. Welm2,5

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630511/

    AND

    Ann Transl Med. 2014 Jun; 2(6): 60.
    PMCID: PMC4200660

    Do metformin a real anticarcinogen? A critical reappraisal of experimental data
    Vladimir N. Anisimovcorresponding author

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032293/

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